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Clindamycin vaginal cream
Cream option for Bacterial Vaginosis treatment in those intolerant to Metronidazole.
Clindamycin vaginal cream
1 tube (40g)
Full course
$104.99
$104.99
Incl. Rx and shipping
Why choose Clindamycin vaginal cream
- Ideal for sensitive users – Suitable for those who may have intolerances to oral medications.
- Proven effectiveness – Effective in treating bacterial vaginosis with targeted action.
- Local treatment – Applied directly to the infection site, reducing side effects.
- Fewer side effects – Lower risk of digestive side effects compared to oral antibiotics.
Good to know*
- Common side effects include vaginal irritation and itching.
- Apply before bed for best results.
- Avoid using tampons or douching during treatment to prevent reduced effectiveness.
Delivery & discretion
- Free shipping on all orders
- Delivery in 2-3 working days
- Need it quick: priority shipping option available in checkout
- Comes in plain packaging
Our service
- No insurance needed
- No in-person doctor visit needed with our quick online consultation
- No prescription needed
- Reviewed by US-licensed physicians
- Dispensed from US -licensed pharmacy
- FDA-approved medication
How to use
Clindamycin vaginal cream
Once daily
Apply one applicatorful (5 grams) of cream once daily for 3 or 7 days.
Use this medicine at bedtime to reduce the likelihood of it leaking out during the day.
Use applicator
Fill the applicator with the gel until the marked line.
Gently insert the applicator into the vagina as far as it feels comfortable.
Push on the plunger to release all the gel into the vagina.
Short course
You should notice an improvement in your symptoms within a few days.
Use this cream for 3 or 7 days in a row, depending on your doctor's instructions.
Key facts
Clindamycin vaginal cream
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Used for
Treats bacterial vaginosis, restoring balance in vaginal flora.
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How to use it*
Apply one full applicator of cream once daily, typically at bedtime, for 3–7 days as prescribed.
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How long to work
Symptoms usually improve within 1–2 days, with full resolution in 3–7 days of treatment.
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Common side effects*
Vaginal irritation, itching, burning, and stomach upset.
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Who should not take it*
Avoid if you have allergies to Clindamycin or lincomycin, or if you are pregnant/breastfeeding.
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Interactions*
Avoid using with other vaginal treatments to ensure effectiveness.
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Generic/branded
Generic: Clindamycin.
Brand: Cleocin.
*Always consult the patient leaflet for comprehensive information.
Clindamycin vaginal cream FAQs
What is Clindamycin vaginal cream used for?
Clindamycin vaginal cream is used to treat vaginal infections, such as bacterial vaginosis (BV). Symptoms of BV include unusual discharge, a fishy odor, and vaginal discomfort. Clindamycin works by stopping the growth of bacteria.
Clindamycin vaginal cream is approved by the FDA. At SpeedyHealth, our doctors are able to prescribe this medicine after you complete an online consultation for BV.
How does Clindamycin vaginal cream work?
Clindamycin phosphate, the active ingredient in this vaginal cream, works by stopping bacteria from making the proteins they need to grow and multiply. It does this by attaching to a specific part of the ribosome, the cell's protein-making machinery.
Clindamycin mainly slows the growth of bacteria rather than killing them.
What are the benefits of using Clindamycin vaginal cream?
There are many benefits of using Clindamycin cream to treat BV:
Localised application
Since the cream is applied directly into the vagina, it acts locally, which minimizes the risk of side effects compared to oral antibiotics.
Convenient dosing
This medicine is applied once daily at bedtime, making it easy for patients to incorporate it into their daily routine.
Safe for patients
This vaginal cream is generally well-tolerated and is a good option for people who can’t take oral antibiotics.
Less chance of interactions
As a topical cream, there is a lower risk of Clindamycin interactions.
How effective is Clindamycin vaginal cream?
Clindamycin vaginal cream is effective in treating infections like bacterial vaginosis.
In a clinical trial of 134 patients, 65 patients were allocated to receive treatment with 5g of Clindamycin 2% vaginal cream and 69 patients received a placebo cream.
At the follow-up evaluation, the results showed that 77% of patients who received Clindamycin experienced complete cure or improvement of BV symptoms compared to only 25% of patients who received the placebo.
How to use
How and when should I use Clindamycin vaginal cream?
To treat BV, the recommended dose is one applicatorful (5 grams) of cream applied inside the vagina once daily, at bedtime, for either 3 or 7 consecutive nights. Using this medicine at bedtime reduces the chance of it leaking out during the day.
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What if I miss a dose?
If you forget a dose and are just a few hours late, use it right away. However, if it is nearly time for your next application, skip the missed dose and apply your next dose at your usual time. Do not use a double dose to make up for a missed dose.
How long does Clindamycin vaginal cream take to work?
This medicine starts working as soon as you use the first dose. The peak concentration of the medication is reached approximately 10 hours after the dose. You should notice your symptoms improving within a few days of using this medicine and complete resolution within 7 days. However, if your infection worsens or symptoms don’t resolve, speak to your doctor.
How long should I use Clindamycin vaginal cream for?
Use this cream for 3 or 7 days in a row, depending on your doctor's instructions. Make sure to finish the entire treatment, even if you start feeling better before it’s done. If you stop early, the infection might not go away completely or could come back.
Safety & side effects
Who can and cannot use Clindamycin vaginal cream?
This cream is an effective option for many women; however, it may not be suitable for everyone.
Who can use it?
Clindamycin vaginal cream is suitable for adult women suffering from bacterial vaginosis who prefer using a localised vaginal treatment.
Who cannot use it?
Do not use this cream if you are allergic to Clindamycin, Lincomycin or any of the other ingredients of this medicine. You should also avoid this medicine if you have a history of inflammatory bowel disease or colitis linked to taking antibiotics.
Speak to your doctor before taking this medicine if you:
- Have diarrhea or usually get diarrhea when taking antibiotics
- Are currently pregnant
- Are breastfeeding
- Currently, have your period
If you currently have your period, you must wait until your period has finished before starting this medication. This is because menstrual bleeding can reduce the absorption and interfere with the effectiveness of the medication.
Dr. Adrian Rawlinson
Supervising Physician
What lifestyle changes should I make while using the Clindamycin vaginal cream?
It’s important to make certain lifestyle changes to ensure this medicine is effective:
Use effective contraception
Clindamycin vaginal cream contains a mineral oil which can weaken latex or rubber products such as condoms or diaphragms. Do not rely on condoms or contraceptive diaphragms when using this medicine and for 72 hours following treatment. Speak to your doctor about alternative contraceptives.
Avoid sexual activity
Avoid sexual intercourse while using this medicine, as the cream may reduce the effectiveness of some contraceptives, and sexual activity can irritate the area or interfere with healing.
Maintain good hygiene
Make sure to wash your genital area gently with mild soap and water. Avoid using scented soaps, wipes, or sprays, as these can disrupt your natural vaginal flora.
Wear breathable underwear
Wear cotton underwear or other breathable fabrics to help keep the vaginal area dry. Avoid tight-fitting underwear as this can trap moisture.
Avoid douching
Avoid douching, as this can disturb the normal vaginal balance and hinder the treatment progress.
What are the side effects of Clindamycin vaginal cream?
Like many medicines, Clindamycin can also cause some side effects, although not everyone experiences them.
Common side effects:
Some common clindamycin vaginal cream side effects that could affect up to 1 in 10 people include:
- Vaginal thrush
- Fungal infections
- Headaches or dizziness
- Changes in taste
- Cough, cold, or sore throat
- Stomach-ache
- Diarrhea or constipation
- Nausea and vomiting
- Itchy skin or a rash
- Back pain
- Urinary tract infections
- Vaginal pain, swelling, or discharge
Uncommon side effects:
Some uncommon side effects that may affect up to 1 in 100 people include:
- Bacterial infections
- Loss of balance
- Nosebleeds
- Upset stomach
- Bad breath
- Gas
- Skin redness
- Pain when urinating or pelvic pain
- Vaginal infection
If you get any side effects, talk to your doctor. This includes any possible side effects not listed here. For a full list of side effects, consult the patient information leaflet.
What interacts with Clindamycin vaginal cream?
This medicine can interact with other prescription medicines, over-the-counter drugs, vitamins, and natural products. Tell your doctor about all other medicines you use.
Clindamycin may increase the effects of drugs used during surgery that help relax muscles. Tell your healthcare professional that you are using Clindamycin if you are due to have any medical procedures.
Avoid using Clindamycin together with Erythromycin, as they can counteract each other's effects.
Do not use any other vaginal products without informing a healthcare professional.
This is not a complete list of interactions. For a full list of drug interactions, visit drugs.com.
What safety advice should I follow while using Clindamycin vaginal cream?
The safety information to follow when taking this medicine can be found in the table below:
| Category | Safety | Advice |
|---|---|---|
| Alcohol | Safe | This medicine does not directly interact with alcohol. |
| Pregnancy | Consult your doctor | If you are pregnant or planning to become pregnant, consult your doctor before using this medicine. |
| Breastfeeding | Consult your doctor | This medicine may pass into breast milk. Speak to your healthcare provider if you plan to breastfeed. |
| Driving | Safe | This medicine doesn’t affect your ability to drive. |
How should I store Clindamycin vaginal cream?
Storage
Store this cream at a controlled room temperature 68° to 77°F and do not freeze. Avoid heat over 86°F as well as high humidity. Keep this medicine out of the sight and reach of children.
Disposal
Do not use this medicine after the expiry date stated on the tube. Do not throw away any unused or expired medicines via wastewater or household waste. Take them to a pharmacy to dispose of safely. This will help to protect the environment.
Buying Clindamycin vaginal cream
Can I buy Clindamycin vaginal cream over the counter?
No, you cannot buy this medicine over the counter. You need a prescription from a doctor to purchase this medicine. This is so that a doctor can determine if this cream is suitable for you.
If you require a prescription, fill out our online consultation form; it is a quick and easy process. If one of our doctors approves of your prescription, you will receive it electronically.
Can I buy Clindamycin vaginal cream online?
Yes, you can buy Clindamycin vaginal cream online from SpeedyHealth. All you have to do is:
- Complete a quick online consultation. It only takes 5-10 minutes.
- Our doctor will review the form to ensure the medicine is right for you.
- Upon approval, an e-prescription will be issued to you.
- Our licensed pharmacy will dispatch the medicine in discreet packaging and send you the tracking details. We offer free doorstep delivery, so you do not have to pay for shipping.
Your privacy is our top priority. SpeedyHealth uses secure, encrypted transactions and complies with USA medical standards to maintain confidentiality.
How much does Clindamycin vaginal cream cost?
The price of Clindamycin vaginal cream at SpeedyHealth includes everything you need:
- Free online consultation
- Free prescription
- Free doorstep delivery
At SpeedyHealth, this gel starts at $104.99
Our pricing is transparent, with no hidden fees. Order today and benefit from our complete, all-inclusive service.
What are the alternatives to Clindamycin vaginal cream?
If this medicine is not right for you, there are other options for treating BV. These include Metronidazole vaginal gel or Tinidazole tablets.
| Feature | Metronidazole | Clindamycin | Tinidazole |
|---|---|---|---|
| Route | Gel (intravaginal) or Tablets (oral) | Cream (intravaginal) | Tablets (oral) |
| Treatment duration |
|
3 or 7 days | 5 days |
| Usage |
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Apply 5g at bedtime | Take 1g once daily with food |
| Effectiveness | 77% cure rate | 91% cure rate | |
| Best for | Patients needing flexible options (oral or vaginal) | Patients preferring local treatment with fewer doses | Patients seeking simple, once-daily oral medication |
| Pricing from | $44.99 | $104.99 | $84.99 |
Why should I choose SpeedyHealth?
Here’s why you should choose SpeedyHealth to manage your medicines easily:
- Our licensed doctors help manage your consultations and prescriptions.
- No face-to-face consultations or lengthy wait times for medication approvals. At SpeedyHealth, everything is handled online, and all information is kept confidential.
- Our dedicated customer support team is ready to help you at the click of a button.
- You can manage your prescriptions easily through our secure platform.
Medically reviewed by Dr. Adrian Rawlinson
Written by our editorial team | Last reviewed January 30, 2026
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