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Used for
Treats excessive sweating (hyperhidrosis) in areas like underarms, palms, and feet.
How to use it*
Apply once a day before bedtime. Use for 3 consecutive days initially, then reduce to once or twice a week.
How long to work
Effective within 24–48 hours after first use, with lasting results for several days.
Common side effects*
Skin irritation, redness, itching, and dryness at the application site.
Who should not take it*
Avoid if you have broken or irritated skin, or sensitivity to aluminum chloride.
Interactions*
No major drug interactions, but avoid using other antiperspirants or harsh skin products on the same area.
Generic/branded
No generic available.
Brand: Drysol Extra Strength.
* Always consult the patient leaflet for comprehensive information.
Drysol antiperspirant is an effective topical treatment, clinically proven to treat excessive sweating, also called hyperhidrosis. It is recommended for people who sweat at rest and haven't found relief with regular deodorants or antiperspirants.
Drysol contains the active ingredient aluminum chloride hexahydrate (ACH). Other over-the-counter antiperspirants may contain this ingredient at a lower concentration, which makes Drysol prescription-only.
Sweat gland
An antiperspirant is applied to the skin's surface
Sweat mixes with the antiperspirant on the surface of the skin
This mixture travels into the sweat glands
A chemical reaction occurs
The antiperspirant forms a 'plug' inside the sweat duct to temporarily reduceperspiration
When antiperspirants containing ACH, such as Drysol, are applied to the surface of the skin, ACH interacts with sweat and forms a plug at the entrance of the skin pore. This acts as a barrier within the sweat duct to stop the flow of sweat to the skin's surface.
This effect is temporary and over time, the plugs naturally break down and are shed with the outer layers of skin or washed away. This is why you have to reapply antiperspirants to maintain their effect.
Your doctor may recommend Drysol for sweating as it has a 98% proven efficacy in controlling sweat and a 30% reduction in sweat volume.
To use it correctly, follow these simple instructions:
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Clean and dry your skin:
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Apply Drysol before bedtime:
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Only apply a small amount:
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Wash it off in the morning:
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To reduce sweating effectively, you should use Drysol consistently. Your doctor will tell you how often to apply this product. Always follow the instructions provided by your healthcare provider or those included in the patient leaflet.
Sweating patterns vary among people. Drysol provides a range of options with three different strengths to choose from:
Here at SpeedyHealth, we currently only offer Drysol® extra strength 20% solution.
Drysol is also available as a Dab-On applicator or a solution. You can choose which product is best for you depending on your sweating intensity and the areas of your body where you experience excessive sweating.
While Drysol can be effective for many people dealing with excessive sweating, it may not be suitable for certain groups of people.
If you are allergic to aluminum chloride hexahydrate or any other ingredients in Drysol, do not use this product. You should also avoid applying this product to open wounds, cuts, or irritated skin. Applying it to damaged areas might cause discomfort or may further irritate your skin.
Drysol may stain clothing or certain fabrics or affect metals. Use it with caution and avoid contact with clothes, bed linen, other fabrics, or metals. Let it dry completely before putting on clothing.
It’s unknown whether Drysol can harm an unborn baby, passes into breast milk, or could hurt a breastfeeding baby. Tell your doctor if you’re pregnant, planning to become pregnant, or are breastfeeding before using this product. Your doctor will weigh the risks and benefits to see if it's suitable for you.
Products that are applied to the skin are unlikely to be affected by other drugs you use. However, you should inform your healthcare provider about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
It is best to avoid using other antiperspirants and deodorants while using Drysol. If you haven’t noticed any improvement while using this product, consult your doctor.
Drysol's side effects most commonly include:
Get medical help if you experience signs of an allergic reaction, these include:
Report side effects and any discomfort you experience to your doctor. Your doctor might suggest changing how often you apply this product or recommend alternative solutions if needed.
You can purchase Drysol for hyperhidrosis online through SpeedyHealth by completing an initial online consultation. Your responses will be assessed by our board-certified doctors to determine the safety of prescribing the medication.
If our doctors believe Drysol is suitable for you, a prescription will be issued to our pharmacy. It will then be prepared and dispatched to your address with discreet packaging.
If our doctors don’t think this is the best medication for you, you won’t be charged.
Medically reviewed by Dr. Adrian Rawlinson
Written by our editorial team | Last reviewed January 13, 2026
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