Doxycycline

Recommended 1st line treatment for chlamydia

FDA Approved Drugs
4.8 11 reviews

Doxycycline

100mg
14 capsules Full course of 7 days
$64.99
$64.99 Incl. Rx and shipping
Why choose Doxycycline
  • Proven effectiveness – Most effective over a longer period.
  • Dual action – Treats both the chlamydia infection and other co-existing bacterial infections.
  • Fewer side effects – Doxycycline is typically better tolerated and easier on the stomach.
Good to know*
  • Common side effects include nausea, upset stomach, and sensitivity to sunlight.
  • Avoid taking it with dairy products, as they may interfere with absorption.
Delivery & discretion
  • Free shipping on all orders
  • Delivery in 2-3 working days
  • Need it quick: priority shipping option available in checkout
  • Comes in plain packaging
Our service
  • No insurance needed
  • No in-person doctor visit needed with our quick online consultation
  • No prescription needed
  • Reviewed by US-licensed physicians
  • Dispensed from US -licensed pharmacy
  • FDA-approved medication
Alternative treatments

How to use

Doxycycline

Take 1 pill daily

Take 1 pill twice a day

Take 100 mg Doxycycline twice daily for 7 days.

Take with a full stomach and water.

Dosage

Tips

Take the capsule at the same time each day.

Don’t lie down for 1 hour after taking to avoid throat irritation.

Visible results

Complete the course

You’ll likely feel better in 2-3 days.

Finish the full 7-day course to prevent the infection from returning.

Key facts

Doxycycline

  • Used for

    Treats chlamydia by killing the bacteria causing the infection.

  • How to use it*

    Take 100 mg twice daily for 7 days with food and a full glass of water. Avoid lying down for 30 minutes after taking.

  • How long to work

    Relief usually begins in 2 to 3 days. Finish the full course.

  • Common side effects*

    Nausea, stomach upset, diarrhea and sensitivity to sunlight.

  • Who should not take it*

    Avoid if pregnant, breastfeeding, or have liver or kidney issues.

  • Interactions*

    Avoid antacids, iron, dairy, and alcohol. May interact with blood thinners.

  • Generic/branded

    Generic: Doxycycline.
    Brand: Vibramycin.

* Always consult the patient leaflet for comprehensive information.

Doxycycline FAQs

What is Doxycycline?

Doxycycline is a broad-spectrum antibiotic that treats bacterial infections and STIs such as chlamydia, syphilis, and gonorrhea.

Doxycycline is approved by the FDA and is sold in tablet, capsule, and liquid form. It is available as a generic drug and under various brand names.

At SpeedyHealth, our doctors are able to prescribe 100mg of Doxycycline capsules after you complete an online consultation.

How does Doxycycline work?

In the US, chlamydia trachomatis (CT) is the most common sexually transmitted infection, with a staggering 1.6 million cases reported back in 2021. If left untreated, it can affect reproductive health, cause ectopic pregnancy (where the fetus is outside of the womb), and infertility.

Doxycycline treats STIs such as chlamydia by stopping the STI-causing bacteria from growing and multiplying. The medicine binds to the bacteria’s protein-producing unit, the 30S ribosomal subunit, and prevents it from producing protein essential for survival and stopping its growth.

What are the benefits of taking Doxycycline?

As Doxycycline targets bacterial infections, there are multiple benefits of taking it to treat illnesses and diseases, for example:

  • It is an effective and recommended treatment for infections such as STIs, acne, and more.
  • It is an easy-to-take antibiotic. As prescribed, take one pill with a glass of water.
  • It can be used as a preventative medicine: Doxycycline is also used as a preventative medicine (Doxy-PEP) to prevent STIs from recurring.
  • It can be taken in different ways. Suppose you find it difficult to swallow the capsules. In that case, you can take Doxycycline by opening the capsules and emptying the contents into a glass containing cold or room-temperature applesauce and drinking it.
How effective is Doxycycline?

Doxycycline is highly effective for treating chlamydia. A 2021 study explored whether Doxycycline helps treat rectal chlamydia in men having sex with men.

The study involved 177 participants who were diagnosed with rectal chlamydia. All participants were men who had sex with men. Seventy participants were given Doxycycline for 7 days, and 65 participants were given a single dose of Azithromycin for a day.

At the 4-week follow-up, the results showcased just how effective Doxycycline is.

Rectal Chlamydia

Doxycycline

100%
Success Rate
70/70 participants successfully treated

Azithromycin

74%
Success Rate
48/65 participants successfully treated

Another study involved 416 women. Out of this, 319 women suffered from both rectal and vaginal chlamydia, 22 women suffered from only rectal chlamydia, and 75 women had only vaginal chlamydia. The women were either given 100 mg Doxycycline twice a day for 7 days or a 1 gm single dose of Azithromycin.

At the 4-week follow-up visit, the results showed that, once again, Doxycycline is a much more reliable treatment choice than Azithromycin.

Women's Treatment Study

416 Total Participants

319 Both Conditions 22 Rectal Only 75 Vaginal Only

Rectal Chlamydia (341 cases)

Doxycycline

95.5%
Success Rate
100mg twice daily
7-day treatment

Azithromycin

78.5%
Success Rate
1g single dose
1-day treatment

Vaginal Chlamydia (394 cases)

Doxycycline

95.4%
Success Rate
100mg twice daily
7-day treatment

Azithromycin

93.5%
Success Rate
1g single dose
1-day treatment

How to use

How and when should I take Doxycycline?

At SpeedyHealth, Doxycycline is available in 100 mg capsules. To treat chlamydia, the recommended Doxycycline dosage is one 100 mg capsule orally twice a day for 7 days.

Before taking Doxycycline, make sure you:

  • Take the capsule at the same time each day for best results.
  • Take the capsule on a full stomach with a glass of water.
  • Do not lie down for at least one hour after taking Doxycycline. This will help you avoid unnecessary irritation in the throat.
What if I miss a dose?

If you miss a dose of Doxycycline, take it as soon as you remember it. Take your next dose at the scheduled time. Do not take a double dose to compensate for the missed dose.

If you find it tough to swallow Doxycycline capsules, place the capsule in a bowl, add a few teaspoons of water, crush the capsule in it, and stir well. You can also add some applesauce to the mixture and drink it.

Dr. Adrian Rawlinson Supervising Physician
How long does Doxycycline take to work?

Once you start taking Doxycycline for STIs, you will usually begin to feel better within 7 to 10 days. It is also important to complete the full course of Doxycycline as prescribed, even if your symptoms start to get better. Stopping the treatment early can cause the infection to return.

If your infection worsens or you develop a new infection, seek medical attention.

How long should I take Doxycycline for?

Depending on your condition, you must take Doxycycline for as long as the doctor has prescribed it. However, the usual treatment course for chlamydia with Doxycycline lasts for 7 days.

Do not stop taking Doxycycline in the middle of treatment, as this can cause unwanted side effects, or the infection may return. It may also make the bacteria more resistant to other antibiotics.

If you are concerned about the treatment duration or any of the medicine’s side effects, discuss this with your healthcare provider.

Safety & side effects

What are the side effects of taking Doxycycline?

Like other medicines, Doxycycline may cause side effects.

Common side effects:

  • Sensitivity to sunlight.
  • Nausea.
  • Stomach pain.
  • Yeast infection.

Serious side effects:

  • Wheeziness or difficulty breathing.
  • Swelling of the face, lips, or eyelids.
  • Severe diarrhea with blood.
  • Skin rash.
  • Severe headache, blurred vision, or permanent vision loss.
  • Blisters on the skin, eyes, and genitalia.

Rare side effects:

  • Feeling anxious.
  • Difficulty swallowing.
  • Ringing or buzzing in the ear.
  • Bowel inflammation.
  • Liver inflammation and damage.
  • Jaundice or pancreatic inflammation.

If you experience any serious or rare side effects, or if your side effects get worse or do not resolve, seek medical attention. To know more about Doxycycline side effects, refer to the Patient Information Leaflet.

Who can and cannot use Doxycycline?

While Doxycycline is generally a safe medicine, it might not be suitable for everyone.

Who can take Doxycycline?

You can take this medicine if you are an adult who has had unprotected sex and wants to reduce the risk of getting STIs such as chlamydia.

Alternatively, you can take Doxycycline if you are an adult suffering from STIs and are looking for an effective treatment.

Who cannot take Doxycycline?

Do not take this medicine if you are allergic to Doxycycline or any other ingredients present in this medicine.

You should also speak to your doctor before taking Doxycycline if any of the following apply to you:

  • you have kidney or liver problems
  • you have myasthenia gravis (a disease that causes muscle weakness)
  • you have porphyria (a rare blood pigment disease)
  • you have or have had systemic lupus erythematosus (a condition that causes joint pain, skin rashes, and fever)
  • you have syphilis
  • you are taking oral retinoids
What lifestyle changes should I make while taking Doxycycline?

While Doxycycline can be useful in treating several bacterial infections, there are a few things you can do to ensure it remains effective:

Lifestyle changes to make while taking Doxycycline for chlamydia

Image 1Practice safe sex

Use protection such as a condom or a dental dam while having sex with your partner to avoid getting infected.

Image 2Communicate with your sexual partner

Inform your sexual partner if you have tested positive for chlamydia so that your partner can do the same for their safety as well.

Image 3Do not share sex toys

Ensure that you are not sharing your sex toys with your partner and vice-versa. Clean them with gentle soap and water every time you use them to prevent chlamydia from getting worse.

What safety advice should I follow while taking Doxycycline?
Category Safety Advice
Alcohol Avoid Avoid drinking alcohol as it may decrease the effectiveness of Doxycycline.
Pregnancy Avoid Doxycycline is contraindicated in pregnancy. It is best to avoid taking this medicine if you are pregnant or planning to become pregnant.
Breastfeeding Avoid Doxycycline affects breastfeeding mothers. It is best to avoid taking this medicine if you are nursing or breastfeeding.
Driving Safe This medicine doesn’t affect your ability to drive.
Sun exposure Avoid This medicine can make your skin sensitive to sunlight. Avoid sun exposure or wear protective clothing to protect your skin from sunlight.
How should I store Doxycycline?

Store Doxycycline at or below 77℉. Keep it out of reach of children and pets and away from direct heat and sunlight. Store it in a dry place, and do not use it past the expiry date.

Do not throw away unused or expired capsules in your garbage bin or flush them down your toilet. Instead, take them to your local pharmacy and ask them to dispose of them.

Your capsule may become discolored or deteriorate over time. If that happens, please contact us for further advice.

Dr. Adrian Rawlinson Supervising Physician

Buying Doxycycline

Can I buy Doxycycline over the counter?

No, you cannot buy Doxycycline over the counter. This antibiotic is only available with a doctor’s prescription.

If you need a prescription, you can complete our short consultation form. If one of our doctors approves it, you will receive your prescription electronically.

Can I buy Doxycycline online?

Yes, you can buy Doxycycline online from SpeedyHealth. All you need to do is:

  • Complete a quick online consultation for Doxycycline. It only takes 5-10 minutes.
  • Our doctor will review the form to ensure the medicine is right for you.
  • Upon approval, an e-prescription will be issued to you.
  • Our licensed pharmacy will dispatch the medicine in discreet packaging and send you the tracking details. We offer free doorstep delivery, so you do not have to pay for shipping.

Your privacy is our top priority. SpeedyHealth uses secure, encrypted transactions and complies with USA medical standards to maintain confidentiality.

What are the alternatives to Doxycycline?

Doxycycline is generally preferred for treating chlamydia as it is highly effective. If Doxycycline is not suitable for you, Azithromycin is a good alternative.

Doxycycline vs Azithromycin

CDC first choice

Doxycycline

Effectiveness:

99% cure rate

CDC recommended first-line treatment

CDC status:

First-line treatment

Primary recommended option

Dosing schedule:

Two doses per day

100mg twice daily for 7 days

PRICE :- $64.99

Single-Dose Option

Azithromycin

Effectiveness:

83-95% cure rate

For rectal infections

CDC status:

Alternative treatment

Recommended alternative

Dosing Schedule:

Single 1g dose

Complete treatment in one dose

PRICE :- $64.99

Both Doxycycline and Azithromycin are effective in treating STIs. However, Doxycycline is slightly more effective, has milder side effects, and is less expensive than Azithromycin.

Doctors also do not recommend Azithromycin any longer for bacterial infections due to its bacterial resistance, which makes Doxycycline the better option.

Why should I choose SpeedyHealth?

Here’s why you should choose SpeedyHealth to manage your medicines easily:

  • Our licensed doctors help manage your consultations and prescriptions.
  • No face-to-face consultations or lengthy wait times for medication approvals. At SpeedyHealth, everything is handled online, and all information is kept confidential.
  • Our dedicated customer support team is ready to help you at the click of a button.
  • You can manage your prescriptions easily through our secure platform.

Medically reviewed by Dr. Adrian Rawlinson

Written by our editorial team | Last reviewed January 28, 2026

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Experiences from others

Doxycycline

Speedyhealth

Excellent

4.8/5

11 patients have reviewed Doxycycline on Trustpilot

Verified Jan 03

By Anthony

The meds are above standard

Verified Dec 18

By Durrell E

I received the shipment. Even i order it for 2 day delivery..

Verified Dec 17

By Dale P

Product as described.

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