Vaginal yeast infection

Get relief from itching and irritation within 24 hours with just one dose of Fluconazole.

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  • Prescribed by board-certified physicians
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FDA Approved Drugs
5 3 reviews

Fluconazole

150mg
1 pill Single dose medication
$49.99
1 pill Single dose medication
$49.99
2 pills
$59.99 Save $39.99
$49.99 Incl. Rx and shipping

Why choose Fluconazole

  • Single-dose treatment – Fluconazole requires just one dose for most cases.
  • Proven effectiveness – Clinically proven to treat vaginal yeast infections with high success rates.
  • Quick relief – Provides relief within 24–48 hours of taking the medication.
  • Well-tolerated – Fewer side effects compared to some topical treatments.

Good to know*

  • Common side effects include headache, nausea, and stomach pain.
  • Avoid if you have liver disease or are pregnant.

Delivery & discretion

  • Free shipping on all orders
  • Delivery in 2-3 working days
  • Need it quick: priority shipping option available in checkout
  • Comes in plain packaging

Our service

  • No insurance needed
  • No in-person doctor visit needed with our quick online consultation
  • No prescription needed
  • Reviewed by US-licensed physicians
  • Dispensed from US-licensed pharmacy
  • FDA-approved medication

How to use

Fluconazole

Take a single dose

Take a single dose

Take 1 tablet as a single dose.

Swallow the tablet whole with a glass of water. Tablets can be taken with or without food.

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Relief within 24 hours

You may notice itching and irritation improve within 24 hours. But, it may take a few days to completely clear the infection.

Symptom-free

Symptom-free

The second tablet may be taken after 3 days (72 hours) if symptoms persist or recur. 
If symptoms persist after 7 days, speak to your doctor as you may need alternative treatment.

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Key facts

Fluconazole

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  • Used for

    Treats vaginal yeast infections caused by the Candida fungus.

  • How to use it*

    Take 150 mg as a single oral dose. Usually only one dose is required.

  • How long to work

    Relief often begins within 24–48 hours, with full resolution taking a few days.

  • Common side effects*

    Headache, nausea, stomach pain, dizziness, and diarrhea.

  • Who should not take it*

    Avoid if pregnant or have liver problems.

  • Interactions*

    Can interact with certain antidepressants, steroids and heart medicines. Avoid alcohol as it may increase the risk of side effects.

  • Generic/branded

    Generic: Fluconazole.
    Brand: Diflucan.

* Always consult the patient leaflet for comprehensive information.

About Fluconazole

What is Fluconazole and how does it work?

Fluconazole is an antifungal medication used to treat infections caused by fungi. The most common cause of fungal infections is a yeast called Candida.

It works by blocking a key enzyme that fungi require to make ergosterol, a key component in their cell membranes. Without ergosterol, the fungal cell membrane becomes leaky. This kills the fungi and treats the infection.

Is Fluconazole an antibiotic?

No, Fluconazole is an antifungal. Antifungals are specifically designed to treat fungal infections, while antibiotics are used to treat bacterial infections.

How to use Fluconazole

Who can use Fluconazole?

Fluconazole is recommened for adults with fungal infections like vaginal yeast infections.

You should not take Fluconazole if you are allergic to the active ingredient, or to any of the other ingredients in this medicine.

You should also avoid Fluconazole if you take:

  • antihistamine medicines for allergies (e.g. astemizole, terfenadine)
  • medicines for stomach upsets (e.g. cisapride)
  • medicine to treat mental illnesses (e.g. pimozide)
  • medicines used to treat heart arrhythmias (e.g. quinidine)
  • antibiotics (e.g. erythromycin)
  • medicines for malaria (e.g. halofantrine)

Consult your doctor before taking this medicine if you have any of the following medical conditons:

  • liver or kidney problems
  • heart disease, including heart rhythm problems
  • abnormal levels of potassium, calcium or magnesium in your blood
  • adrenal insufficiency (sypmtoms include long lasting fatigue, muscle weakness, loss of appetite, weight loss, abdominal pain)

For a complete list of contraindications and possible medicine interactions, consult the patient information leaflet.

Safety & side effects

What are the possible side effects?

Common side effects:

  • Headache
  • Stomach discomfort or diarrhea
  • Nausea or vomiting
  • Increases in blood tests of liver function

Serious side effects

Stop taking Fluconazole and seek immediate medical attention if you experience any of the following side effects:

  • A high body temperature and enlarged lymph nodes
  • An allergic reaction (symptoms include wheezing, difficulty breathing, chest tightness, swelling of eyelids, face or lips, a widespread itchy rash)
  • Liver problems (symptoms include tiredness, loss of appetite, vomiting, yellowing of the skin or the whites of the eyes)
  • Severe skin peeling, blistering and/or mouth sores

Buying Fluconazole

Can I buy Fluconazole online?

Yes, you can buy Fluconazole antifungal tablets online at SpeedyHealth after completing our free online consultation for vaginal yeast infections.

How do I get a prescription for Fluconazole?

Since Fluconazole is a prescription-only medicine, you'll need to complete a quick online consultation. This helps our doctors make sure it's safe and suitable for you before prescribing. The process is simple, fast, and all done from the comfort of your home.

Medically reviewed by Dr. Adrian Rawlinson

Written by our editorial team | Last reviewed January 22, 2026

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