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Promethazine
Promethazine eases nighttime allergy symptoms and helps you sleep, taking effect in under an hour.
Promethazine
25mg
30 pills
Suitable for 30 days
$49.99
30 pills
Suitable for 30 days
$49.99
60 pills
Suitable for 60 days
$64.99
90 pills
Suitable for 90 days
$79.99
$49.99
Incl. Rx and shipping
Why choose Promethazine
- Dual benefit – Helps with hay fever and sleep in one nightly dose.
- More sedating – Better for nighttime symptoms that keep you awake.
- Covers more symptoms – Also helps with nausea, coughing, and sinus discomfort.
- Backup option – Useful when other allergy meds don’t provide full relief.
- Cheaper generic – Same active ingredient as Phenergan.
Good to know*
- Common side effects include drowsiness, dry mouth, and dizziness
- Take only at night unless advised otherwise
- Avoid alcohol and other sedatives while using
- May impair driving or alertness the next day
Delivery & discretion
- Free shipping on all orders
- Delivery in 2-3 working days
- Need it quick: priority shipping option available in checkout
- Comes in plain packaging
Our service
- No insurance needed
- No in-person doctor visit needed with our quick online consultation
- No prescription needed
- Reviewed by US-licensed physicians
- Dispensed from US -licensed pharmacy
- FDA-approved medication
How to use
Promethazine
Take at nighttime
Take one 25 mg tablet in the evening. Promethazine works best when taken at the same time each night for allergy relief and improved sleep. .
Relief in 30–60 minutes
You may start to feel symptom relief and an improvement in sleep within an hour. Effects last around 8–12 hours.
Use with caution
Avoid alcohol and driving after taking. Its sedative effect can last into the next morning, especially in new users or older adults.
Key facts
Promethazine
-
Used for
Hay fever symptoms with nighttime discomfort.
-
How to use it*
Take one 25 mg tablet at night; only as needed.
-
How long to work
Starts in 30–60 minutes; lasts up to 12 hours.
-
Common side effects*
Drowsiness, dry mouth, dizziness.
-
Who should not take it*
Avoid if you have severe breathing disorders.
-
Interactions*
Avoid alcohol, opioids, and other CNS depressants
-
Generic/branded.
Generic: Promethazine.
Brand: Phenergan
* Always consult the patient leaflet for comprehensive information.
Promethazine FAQ's
What is Promethazine and what is it used for?
Promethazine is a sedating antihistamine used to relieve hay fever and other allergy symptoms. It works by blocking the effects of histamine, helping to reduce sneezing, itchy or watery eyes, a runny nose, and skin irritation. It can also be used to relieve motion sickness, vertigo, or short-term insomnia.
How to use
Who can use Promethazine?
Anyone aged 12 or older with hay fever or allergy symptoms can take promethazine.
Do not take promethazine if you:
- Have had an allergic reaction to promethazine in the past
Use with caution if you:
- Have eye problems such as glaucoma
- Have difficulty breathing (asthma or lung infections)
- Have epilepsy
- Have kidney or liver problems
For a complete list of precautions and medicine interactions, consult the patient information leaflet.
How long does it take to work?
Promethazine typically starts to work within 20 minutes, with peak effect usually seen around 1 to 2 hours after taking it.
Safety & side effects
What are the possible side effects?
Common side effects include:
- Drowsiness
- Dizziness
- Headaches
- Nightmares
Stop taking and speak to a doctor immediately if you experience:
- Severe drowsiness
- Confusion
- Seizures
- Light-headedness
- Irregular heartbeat
- Fever or sudden feeling of weakness
Seek immediate medical attention if you experience symptoms of an allergic reaction such as:
- Breathlessness
- Skin rash
- Swelling in the face
What should I avoid while taking Promethazine?
Promethazine is a sedating antihistamine. Be cautious when driving or operating machinery. Avoid exposure to sunlight as it may increase skin sensitivity.
Buying Promethazine
Do I need a prescription?
Yes. Promethazine is a prescription-only medicine, which means it can only be supplied after a doctor has confirmed it is safe and appropriate for you.
How do I buy Promethazine online from SpeedyHealth?
You must complete an online consultation form as promethazine is a prescription-only medication. It’s a quick and easy process that allows our doctors to ensure this medicine is safe and suitable for you to take.
Medically reviewed by Dr. Adrian Rawlinson
Written by our editorial team | Last reviewed January 15, 2026
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