Deciding to quit is a big step - and you're not alone. Take control with Varenicline for a smoke-free life.
Varenicline is a prescription medication clinically tested to help you quit smoking. It has already helped millions of people successfully stop smoking.
Clinical trials* have proven that Varenicline is highly effective in helping people quit smoking:
* A 24-week study involving 114 participants, randomly assigned to receive either 1 mg of Varenicline or a matched placebo. The results showed significantly higher continuous abstinence rates in the Varenicline group compared to the placebo group: 50.0% vs. 16.9% at week 12, and 48.7% vs. 14.3% at week 24.
Was on it for 6 weeks. It literally made me forget to smoke. No cravings at all. Made quitting a cake walk. Absolutely no physical response from quitting! It's literally a godsend. I tell every smoker I know to get on it. One actually did. Smoked for 50 years. He ran out of cigarettes while being on it for about 4.5 weeks and just never bought another pack. please get on it!! You won't regret it!
R.D.
This is only my 2nd day, but was a pack and 1/2 daily smoker for 45 years. I could have never lasted more than a few hours - never 2 days before- I am quite impressed with the drug and myself - the occasional urge is fleeting . I had a few weird dreams , but nothing that would make me stop the prescription for sure. I am amazed quite frankly that I don't want to tear someone's head off !
Andy M.
It started with the cigarettes losing their effectiveness, then the cravings themselves got milder. One day I just quit. It was abrupt, literally in the middle of smoking I just stopped. There was no pang of satisfaction, even the smell was just gross. The pointlessness of it really hit me like a tonne of bricks and that was that.
JoCruz
I tried it for the first time, for a month, since my insurance only covered for a month, relapsed.
Tried again in a year, recall happened, only did it for a month, relapsed. Tried 6 months ago, did for two months, now im 6+ months nicotine free.
I don't think i could've done it without that shit. Good luck!
Bobby
I loved smoking, 47 days now taking varenicline and I despise it. Wish I would've done it 15 years ago. I actually feel like a normal person on varenicline. 40 days cig free and I feel amazing. A little insomnia and a little nausea during the starter pack but nothing unbearable. Definitely worth the trade off of not smelling like a ashtray.
Dw
Option 1: pick a quit date
Start taking Varenicline 7 days before the quit date and stop smoking on the decided quit date.
Option 2: flexible quit date
Take Varenicline from day 1 to day 7, then choose a quit date between day 8 and day 35. Make sure you stop smoking on the decided quit date.
Dosage schedule
1st steps
1st week
2nd week
1 month
3 months
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Used for
Quitting smoking by reducing cravings and withdrawal symptoms.
How to use it*
Multiple regimes. Typically two tablets daily.
How long to work
Effects may be noticeable within 1–2 weeks. Full benefits typically after 12 weeks.
Common side effects*
Nausea, constipation, diarrhea, sleep problems and vomiting.
Who should not take it*
Avoid if you have mental health issues, kidney problems, heart conditions, or blood vessel disorders.
Interactions*
Avoid excessive alcohol and other nicotine replacement therapies.
Generic/branded
Generic: Varenicline.
Brand: Chantix
*Always consult the patient leaflet for comprehensive information.
Varenicline is a prescription medicine that helps adults quit smoking.
Varenicline is different from other smoking cessation medicines. Varenicline works differently from other medicines used to quit smoking. Unlike nicotine patches or gum that replace nicotine, Varenicline specifically targets nicotine receptors in your brain. This helps to reduce cigarette cravings and minimize withdrawal symptoms.
Varenicline’s brand-name medicine, Chantix, was manufactured by Pfizer and was approved by the FDA in 2006. However, Pfizer discontinued the production of Chantix in 2021. The FDA approved generic Varenicline in the US in the same year.
At SpeedyHealth, our doctors are able to prescribe Varenicline for adults who are motivated to quit smoking.
Varenicline works in two ways. It helps in quitting smoking by reducing the craving to smoke and depriving the smoker of the pleasure associated with smoking.
For those who are determined to quit smoking, Varenicline offers many benefits:
Quit smoking medicine Varenicline is extremely efficient in helping smokers quit smoking.
A clinical study was conducted with 155 participants over 24 weeks to analyze the effects of using Varenicline to stop smoking. The participants used tobacco cigarettes and e-cigarettes at least once a day. For the first 12 weeks, the study was divided into two groups, where some participants were given Varenicline, and others were given a placebo.
Both groups were monitored for the next 12 weeks and also received counseling for smoking addiction.
The study found that:
Varenicline begins to work as soon as you start to take it. However, it might take a few weeks to notice the effects.
You will notice signs of improvement when it comes to your smoking addiction. These include:
There are two ways you can take Varenicline. The information below explains how to take Varenicline for the best results.
Pick a quit date
Keep a flexible quit date
0.5 mg tablets (white) - starter pack
1 mg tablets (blue) - maintenance pack
Dosage schedule
Take Varenicline with a full glass of water.
Days 1-3
Take one 0.5 mg tablet daily.
Days 4-7
Take one 0.5 mg tablet twice a day
(Once in the morning, once in the evening)
Day 8 onwards
Take one 1 mg tablet twice a day
(Once in the morning, once in the evening)
Missed a dose?
Take it as soon as you remember it.
Almost time for your next dose?
Skip the missed dose and continue with regular dosing schedule.
If you slip up and begin smoking again after taking Varenicline, do not get demotivated. Just try again. Usually, people need to take Varenicline for a few weeks before the tablet actually begins working for them.
Varenicline needs to be taken for up to 12 weeks.
If by week 12, you have completely stopped smoking, our doctor may prescribe a maintenance dose of Varenicline for another 12 weeks to keep you off smoking.
To make quitting smoking easier, you can also try the gradual approach to abstain from using a cigarette.
Weeks 1-4
Start taking Varenicline and reduce smoking by 50% from baseline.
20 cigarettes
10 cigarettes
Weeks 5-8
Continue taking Varenicline and reduce smoking by another 50%.
10 cigarettes
5 cigarettes
Weeks 9-12
Continue taking Varenicline and try to stop smoking completely.
5 cigarettes
0 cigarettes
Weeks 13-24
If you have successfully stopped smoking, stay on Varenicline’s maintenance dose to maintain abstinence from smoking.
If by week 12, you have not been able to stop smoking completely, it is recommended that you try taking Varenicline again.
Taking Varenicline to stop smoking is one of the biggest lifestyle decisions you will ever make. To get the most out of this medication and improve your chances of success, it's important to consider the following lifestyle changes:
Store Varenicline at room temperature between 59℉ and 86℉. Do not use Varenicline tablets past their expiry date. Keep this medicine out of the reach of children and pets.
Do not throw away unused or expired Varenicline in your household waste. Return it to your nearest pharmacy for proper disposal.
You should avoid taking this medication if you are allergic to the active ingredient or any other ingredients in this medicine. Before you take Varenicline, inform us in your consultation form if you:
Special precautions need to be taken in the following events before taking Varenicline:
Varenicline is highly effective for smokers committed to quitting, but it may not be suitable for everyone.
Varenicline is suitable for individuals over 18 who are addicted to smoking and motivated to quit. It is recommended for people who have struggled to quit using other methods and are looking for an alternative.
Like all medicines, Varenicline may cause some side effects.
Varenicline can have some serious side effects. Stop taking the medicine and seek immediate medical attention if the following side effects persist or worsen:
This is not a complete list of Varenicline’s side effects. For a full list, please refer to the Patient Information Leaflet.
Nausea is one of the most common side effects of taking Varenicline. It will usually resolve within a few days of starting the medicine. But if nausea persists, talk to us about dose reduction.
Varenicline doesn’t interact with a lot of medicines. However, inform us in your consultation form if you are currently on or planning to take any of the following medicines:
When taking Varenicline, it's important to follow these safety guidelines:
| Category | Safety | Advice |
|---|---|---|
| Alcohol | Safe | It is safe to drink alcohol while taking Varenicline. But be cautious if you experience hallucinations or paranoia while taking this medicine, as alcohol may worsen the side effects. |
| Pregnancy | Use caution | It is not known if Varenicline affects pregnancy. Let us know in your consultation form if you are pregnant or planning to become pregnant so that our doctor can advise you accordingly. |
| Breastfeeding | Use caution | It is not known if Varenicline passes into breast milk. Let us know in your consultation form if you are breastfeeding or planning to breastfeed so that our doctor can advise you accordingly. |
| Driving | Avoid | Varenicline may affect driving or operating heavy machinery. Avoid driving or operating heavy machinery until you are not sure of how Varenicline affects you. |
No, you cannot buy Varenicline over the counter. It's a prescription-only medication. You will need a valid prescription from a licensed healthcare professional to purchase the medicine.
You can simply fill out our short consultation form and get an e-prescription from one of our licensed doctors.
Yes, you can buy Varenicline online from SpeedyHealth. Ordering this medicine online is convenient and straightforward. All you need to do is follow these four simple steps:
Your privacy is our top priority. SpeedyHealth uses secure, encrypted transactions and complies with USA medical standards to maintain confidentiality.
Here’s why you should choose SpeedyHealth for better management of your health:
Medically reviewed by Dr. Adrian Rawlinson
Written by our editorial team | Last reviewed January 15, 2026
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